ELISA & EIA

ELISA

With our LUCIO ®-Drug ELISAs, we offer over 20 CE certified assays for drugs and their metabolites in order to practically examine all sample types relevant to a forensic laboratory. The drastic reduction of the detection limits, as well as the sharp decline in positive rates in the examined samples, require a cost-effective screening test with particularly high sensitivity and high reliability in the field of the cut off region.

The LUCIO ®-Drug ELISA tests meet all the requirements listed above and provide an easy and inexpensive way to accurately analyse the samples before extensive (time-consuming) chromatographic / mass spectrometric assays.

LUCIO ®-Drug ELISAs are suitable for drug analysis in almost all to be examined samples such as urine, saliva, etc. Thanks to the assay configuration, the tests require an implementation of only two steps, without the use of secondary antibodies

EIA

With our LUCIO ® homogeneous enzyme immunoassays (EIA), we have 32 certified to CE assays for the detection of drugs and their metabolites in urine or saliva.

LUCIO® Drug EIA Saliva

For the detection of different drugs in saliva parameters we offer LUCIO ®-Oral Fluid Drug EIA kits for the 15 most common parameters. 

LUCIO® Drug EIA Urine

For drug analysis in urine, our range of reagents have calibrators and controls for the detection of 17 different analytes. According to the requirements of forensic /toxicology laboratories, we offer calibrators in four concentrations (low, cut-off, intermediate and high) and two additional controls. In addition, some of our calibrators and controls are also available as multi-calibrator.

EIA Principle:

EIA principle: The LUCIO ® - EIAs are homogeneous enzyme immunoassays of ready-to-use liquid reagents. The assay is based on a competitive reaction between the drug in the sample and the enzyme glucose-6 -phosphate dehydrogenase (G6PDH) to the fixed number of the binding sites of the specific antibody. In the absence of the free drug in the sample, the drug labeled with the drug G6PDH is bound by the specific antibody and the enzyme activity is inhibited. This property allows a relationship between the concentration of drug in the urine and the enzyme activity. G6PDH activity is determined by the conversion of NAD + to NADH spectrophotometrically at 340 nm

Automation:

LUCIO ®-Drug EIA kits are suitable for use in all common laboratory machines., We can assist you with the planning of the automation in the technical implementation as well as in the validation and preparation of analytical protocols for our EIAs.